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Maternal Treatment with Metformin Persistently Ameliorates High-Fat Diet-Induced Metabolic Symptoms and Modulates Gut Microbiota in Rat Offspring

A maternal high-fat (HF) diet has long-term deleterious effect on offspring. This study aims to evaluate whether maternal metformin (MT) treatment ameliorates the adverse effects of maternal HF diet on offspring and the role of gut microbiota in it. Pregnant Sprague-Dawley rats were randomly assigne...

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Detalles Bibliográficos
Autores principales: Song, Lin, Cui, Jiaqi, Hu, Shuyuan, Wang, Rui, Li, Hongbao, Sun, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460832/
https://www.ncbi.nlm.nih.gov/pubmed/36079869
http://dx.doi.org/10.3390/nu14173612