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Profiling of Tregs across tissues reveals plasticity in ST2 expression and hierarchies in tissue-specific phenotypes

Foxp3(+) regulatory T cells (Tregs) are critical mediators of peripheral tolerance and immune homeostasis and exert tissue-specific functions. In many nonlymphoid tissues, Tregs show enriched expression of the IL-33 receptor ST2. Through comprehensive profiling of murine ST2(+) and ST2(-) Tregs, we...

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Detalles Bibliográficos
Autores principales: Spath, Sabine, Roan, Florence, Presnell, Scott R., Höllbacher, Barbara, Ziegler, Steven F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460833/
https://www.ncbi.nlm.nih.gov/pubmed/36093048
http://dx.doi.org/10.1016/j.isci.2022.104998