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Cortical and subcortical grey matter atrophy in Amyotrophic Lateral Sclerosis correlates with measures of disease accumulation independent of disease aggressiveness

There is a growing demand for reliable biomarkers to monitor disease progression in Amyotrophic Lateral Sclerosis (ALS) that also take the heterogeneity of ALS into account. In this study, we explored the association between Magnetic Resonance Imaging (MRI)-derived measures of cortical thickness (CT...

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Detalles Bibliográficos
Autores principales: Dieckmann, Nora, Roediger, Annekathrin, Prell, Tino, Schuster, Simon, Herdick, Meret, Mayer, Thomas E., Witte, Otto W., Steinbach, Robert, Grosskreutz, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9460837/
https://www.ncbi.nlm.nih.gov/pubmed/36067613
http://dx.doi.org/10.1016/j.nicl.2022.103162