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Positional motif analysis reveals the extent of specificity of protein-RNA interactions observed by CLIP

BACKGROUND: Crosslinking and immunoprecipitation (CLIP) is a method used to identify in vivo RNA–protein binding sites on a transcriptome-wide scale. With the increasing amounts of available data for RNA-binding proteins (RBPs), it is important to understand to what degree the enriched motifs specif...

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Detalles Bibliográficos
Autores principales: Kuret, Klara, Amalietti, Aram Gustav, Jones, D. Marc, Capitanchik, Charlotte, Ule, Jernej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9461102/
https://www.ncbi.nlm.nih.gov/pubmed/36085079
http://dx.doi.org/10.1186/s13059-022-02755-2