Inhibition of the IRE1/JNK pathway in renal tubular epithelial cells attenuates ferroptosis in acute kidney injury

Backgroud: Ferroptosis is a form of regulated cell death in ischemia-reperfusion (I/R) injury models. Acute kidney injury (AKI) induced by I/R injury can result in cell death, and subcellular structural changes, including expansion of the endoplasmic reticulum (ER), mitochondrial shrinkage, and othe...

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Detalles Bibliográficos
Autores principales: Liang, Yan, Liu, Zhenjie, Qu, Lingyun, Wang, Yingzi, Zhou, Yali, Liang, Lulu, Guo, Yanhong, Tang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9461286/
https://www.ncbi.nlm.nih.gov/pubmed/36091771
http://dx.doi.org/10.3389/fphar.2022.927641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9461286/
https://www.ncbi.nlm.nih.gov/pubmed/36091771
http://dx.doi.org/10.3389/fphar.2022.927641

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