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Integrative network analysis of circular RNAs reveals regulatory mechanisms for hepatic specification of human iPSC-derived endoderm

BACKGROUND: Human-induced pluripotent stem cell (hiPSC)-derived functional hepatic endoderm (HE) is supposed to be an alternative option for replacement therapy for end-stage liver disease. However, the high heterogeneity of HE cell populations is still challenging. Hepatic specification of definiti...

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Detalles Bibliográficos
Autores principales: Bai, Fang, Duan, Jinliang, Yang, Daopeng, Lai, Xingqiang, Zhu, Xiaofeng, He, Xiaoshun, Hu, Anbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9461288/
https://www.ncbi.nlm.nih.gov/pubmed/36076262
http://dx.doi.org/10.1186/s13287-022-03160-z