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PHGDH Inhibits Ferroptosis and Promotes Malignant Progression by Upregulating SLC7A11 in Bladder Cancer

Background: Bladder cancer (BCa) is a prevalent urologic malignancy that shows a poor prognosis. Abnormal metabolism and its key genes play a critical role in BCa progression. In this study, the role played by PhosphoGlycerol Dehydrogenase (PHGDH), an important molecule of serine metabolism, was inv...

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Detalles Bibliográficos
Autores principales: Shen, Liliang, Zhang, Junfeng, Zheng, Zongtai, Yang, Fuhan, Liu, Shenghua, Wu, Yuan, Chen, Yifan, Xu, Tianyuan, Mao, Shiyu, Yan, Yang, Li, Wei, Zhang, Wentao, Yao, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9461664/
https://www.ncbi.nlm.nih.gov/pubmed/36147463
http://dx.doi.org/10.7150/ijbs.74546