Anionic Lipid Nanoparticles Preferentially Deliver mRNA to the Hepatic Reticuloendothelial System

Lipid nanoparticles (LNPs) are the leading nonviral technologies for the delivery of exogenous RNA to target cells in vivo. As systemic delivery platforms, these technologies are exemplified by Onpattro, an approved LNP-based RNA interference therapy, administered intravenously and targeted to paren...

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Detalles Bibliográficos
Autores principales: Pattipeiluhu, Roy, Arias-Alpizar, Gabriela, Basha, Genc, Chan, Karen Y. T., Bussmann, Jeroen, Sharp, Thomas H., Moradi, Mohammad-Amin, Sommerdijk, Nico, Harris, Edward N., Cullis, Pieter R., Kros, Alexander, Witzigmann, Dominik, Campbell, Frederick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9461706/
https://www.ncbi.nlm.nih.gov/pubmed/35218106
http://dx.doi.org/10.1002/adma.202201095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9461706/
https://www.ncbi.nlm.nih.gov/pubmed/35218106
http://dx.doi.org/10.1002/adma.202201095

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