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Immunogenicity and protective efficacy of a DNA vaccine inducing optimal expression of the SARS-CoV-2 S gene in hACE2 mice

The wide spread of coronavirus disease 2019 (COVID-19) has significantly threatened public health. Human herd immunity induced by vaccination is essential to fight the epidemic. Therefore, highly immunogenic and safe vaccines are necessary to control SARS-CoV-2, whose S protein is the antigenic dete...

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Detalles Bibliográficos
Autores principales: Li, Zhuo-xin, Feng, Sheng, Zhang, He, Zhuang, Xin-yu, Shang, Chao, Sun, Shi-yu, Han, Ji-cheng, Xie, Yu-biao, Zhang, Jin-yong, Wang, Wei, Li, Cheng-hui, Zhao, Guan-yu, Hao, Peng-fei, Ma, Jun-xian, Gao, Yan, Zeng, Jia-qing, Tian, Ming-yao, Ha, Zhuo, Lu, Hui-jun, Jin, Ning-yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462073/
https://www.ncbi.nlm.nih.gov/pubmed/36083350
http://dx.doi.org/10.1007/s00705-022-05562-z