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(2S,3′S,3a’R,5′R,7a’R)-5′-[(E)-5-(Furan-3-yl)-2-methyl­pent-1-en-1-yl]-3-hy­droxy-3′,4,7′-trimethyl-1′,2′,3′,3a’,5′,7a’-hexa­hydro-5H-spiro­[furan-2,4′-inden]-5-one

The title compound, ircinianin, C(25)H(32)O(4), belongs to the sesterterpene tetronic acid compound family and was isolated from the marine sponge Ircinia wistarii. These chemical scaffolds are pharmacologically relevant, since they represent a new class of glycine receptor modulators. The furan rin...

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Detalles Bibliográficos
Autores principales: Majer, Thomas, Schollmeyer, Dieter, Koch, Pierre, Gross, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462169/
https://www.ncbi.nlm.nih.gov/pubmed/36337332
http://dx.doi.org/10.1107/S2414314620015783