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Single-cell RNA-sequencing analysis reveals the molecular mechanism of subchondral bone cell heterogeneity in the development of osteoarthritis

The cellular composition and underlying spatiotemporal transformation processes of subchondral bone in osteoarthritis (OA) remain unknown. Herein, various cell subsets from tibial plateau of patients with OA are identified, and the mechanism of subchondral microstructure alteration is elaborated usi...

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Detalles Bibliográficos
Autores principales: Hu, Yan, Cui, Jin, Liu, Han, Wang, Sicheng, Zhou, Qirong, Zhang, Hao, Guo, Jiawei, Cao, Liehu, Chen, Xiao, Xu, Ke, Su, Jiacan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462384/
http://dx.doi.org/10.1136/rmdopen-2022-002314