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Global epidemiology, genetic environment, risk factors and therapeutic prospects of mcr genes: A current and emerging update

BACKGROUND: Mobile colistin resistance (mcr) genes modify Lipid A molecules of the lipopolysaccharide, changing the overall charge of the outer membrane. RESULTS AND DISCUSSION: Ten mcr genes have been described to date within eleven Enterobacteriaceae species, with Escherichia coli, Klebsiella pneu...

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Detalles Bibliográficos
Autores principales: Mmatli, Masego, Mbelle, Nontombi Marylucy, Osei Sekyere, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462459/
https://www.ncbi.nlm.nih.gov/pubmed/36093193
http://dx.doi.org/10.3389/fcimb.2022.941358