Assemblies of JAG1 and JAG2 determine tracheobronchial cell fate in mucosecretory lung disease

Mucosecretory lung disease compromises airway epithelial function and is characterized by goblet cell hyperplasia and ciliated cell hypoplasia. Goblet and ciliated cell types are derived from tracheobronchial stem/progenitor cells via a Notch-dependent mechanism. Although specific arrays of Notch re...

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Detalles Bibliográficos
Autores principales: Reynolds, Susan D., Hill, Cynthia L., Alsudayri, Alfahdah, Lallier, Scott W., Wijeratne, Saranga, Tan, Zheng Hong, Chiang, Tendy, Cormet-Boyaka, Estelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462471/
https://www.ncbi.nlm.nih.gov/pubmed/35819850
http://dx.doi.org/10.1172/jci.insight.157380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462471/
https://www.ncbi.nlm.nih.gov/pubmed/35819850
http://dx.doi.org/10.1172/jci.insight.157380

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