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Assemblies of JAG1 and JAG2 determine tracheobronchial cell fate in mucosecretory lung disease
Mucosecretory lung disease compromises airway epithelial function and is characterized by goblet cell hyperplasia and ciliated cell hypoplasia. Goblet and ciliated cell types are derived from tracheobronchial stem/progenitor cells via a Notch-dependent mechanism. Although specific arrays of Notch re...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462471/ https://www.ncbi.nlm.nih.gov/pubmed/35819850 http://dx.doi.org/10.1172/jci.insight.157380 |