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Treg suppression of immunity within inflamed allogeneic grafts

CD4(+)Foxp3(+) regulatory T cells (Tregs) restrain inflammation and immunity. However, the mechanisms underlying Treg suppressor function in inflamed nonlymphoid tissues remain largely unexplored. Here, we restricted immune responses to nonlymphoid tissues and used intravital microscopy to visualize...

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Detalles Bibliográficos
Autores principales: Dai, Hehua, Pena, Andressa, Bauer, Lynne, Williams, Amanda, Watkins, Simon C., Camirand, Geoffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462475/
https://www.ncbi.nlm.nih.gov/pubmed/35881490
http://dx.doi.org/10.1172/jci.insight.160579