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Nanoparticles reduce monocytes within the lungs to improve outcomes after influenza virus infection in aged mice

Older people exhibit dysregulated innate immunity to respiratory viral infections, including influenza and SARS-CoV-2, and show an increase in morbidity and mortality. Nanoparticles are a potential practical therapeutic that could reduce exaggerated innate immune responses within the lungs during vi...

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Detalles Bibliográficos
Autores principales: Kelley, William J., Wragg, Kathleen M., Chen, Judy, Murthy, Tushar, Xu, Qichen, Boyne, Michael T., Podojil, Joseph R., Elhofy, Adam, Goldstein, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462478/
https://www.ncbi.nlm.nih.gov/pubmed/35737459
http://dx.doi.org/10.1172/jci.insight.156320