Macrophage miR-149-5p induction is a key driver and therapeutic target for BRONJ

Bisphosphonate-related (BP-related) osteonecrosis of the jaw (BRONJ) is one of the severe side effects of administration of BPs, such as zoledronic acid (ZA), which can disrupt the patient’s quality of life. Although the direct target of skeletal vasculature and bone resorption activity by BPs has b...

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Detalles Bibliográficos
Autores principales: Shen, Xin, Zhu, Weiwen, Zhang, Ping, Fu, Yu, Cheng, Jie, Liu, Laikui, Xu, Rongyao, Jiang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462481/
https://www.ncbi.nlm.nih.gov/pubmed/35993364
http://dx.doi.org/10.1172/jci.insight.159865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462481/
https://www.ncbi.nlm.nih.gov/pubmed/35993364
http://dx.doi.org/10.1172/jci.insight.159865

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