Ligand-independent integrin β1 signaling supports lung adenocarcinoma development

Integrins — the principal extracellular matrix (ECM) receptors of the cell — promote cell adhesion, migration, and proliferation, which are key events for cancer growth and metastasis. To date, most integrin-targeted cancer therapeutics have disrupted integrin-ECM interactions, which are viewed as c...

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Detalles Bibliográficos
Autores principales: Haake, Scott M., Plosa, Erin J., Kropski, Jonathan A., Venton, Lindsay A., Reddy, Anupama, Bock, Fabian, Chang, Betty T., Luna, Allen J., Nabukhotna, Kateryna, Xu, Zhi-Qi, Prather, Rebecca A., Lee, Sharon, Tanjore, Harikrishna, Polosukhin, Vasiliy V., Viquez, Olga M., Jones, Angela, Luo, Wentian, Wilson, Matthew H., Rathmell, W. Kimryn, Massion, Pierre P., Pozzi, Ambra, Blackwell, Timothy S., Zent, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462485/
https://www.ncbi.nlm.nih.gov/pubmed/35763345
http://dx.doi.org/10.1172/jci.insight.154098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462485/
https://www.ncbi.nlm.nih.gov/pubmed/35763345
http://dx.doi.org/10.1172/jci.insight.154098

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