NK cells contribute to reovirus-induced IFN responses and loss of tolerance to dietary antigen

Celiac disease is an immune-mediated intestinal disorder that results from loss of oral tolerance (LOT) to dietary gluten. Reovirus elicits inflammatory Th1 cells and suppresses Treg responses to dietary antigen in a strain-dependent manner. Strain type 1 Lang (T1L) breaks oral tolerance, while stra...

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Detalles Bibliográficos
Autores principales: Brigleb, Pamela H., Kouame, Elaine, Fiske, Kay L., Taylor, Gwen M., Urbanek, Kelly, Medina Sanchez, Luzmariel, Hinterleitner, Reinhard, Jabri, Bana, Dermody, Terence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462493/
https://www.ncbi.nlm.nih.gov/pubmed/35993365
http://dx.doi.org/10.1172/jci.insight.159823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462493/
https://www.ncbi.nlm.nih.gov/pubmed/35993365
http://dx.doi.org/10.1172/jci.insight.159823

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