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Reversal of ciliary mechanisms of disassembly rescues olfactory dysfunction in ciliopathies

Ciliopathies are a class of genetic diseases resulting in cilia dysfunction in multiple organ systems, including the olfactory system. Currently, there are no available curative treatments for olfactory dysfunction and other symptoms in ciliopathies. The loss or shortening of olfactory cilia, as see...

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Detalles Bibliográficos
Autores principales: Xie, Chao, Habif, Julien C., Ukhanov, Kirill, Uytingco, Cedric R., Zhang, Lian, Campbell, Robert J., Martens, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462494/
https://www.ncbi.nlm.nih.gov/pubmed/35771640
http://dx.doi.org/10.1172/jci.insight.158736