Increased expression and accumulation of GDF15 in IPF extracellular matrix contribute to fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic disease of unmet medical need. It is characterized by formation of scar tissue leading to a progressive and irreversible decline in lung function. IPF is associated with repeated injury, which may alter the composition of the extracellular matrix (ECM...

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Detalles Bibliográficos
Autores principales: Radwanska, Agata, Cottage, Christopher Travis, Piras, Antonio, Overed-Sayer, Catherine, Sihlbom, Carina, Budida, Ramachandramouli, Wrench, Catherine, Connor, Jane, Monkley, Susan, Hazon, Petra, Schluter, Holger, Thomas, Matthew J., Hogaboam, Cory M., Murray, Lynne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462497/
https://www.ncbi.nlm.nih.gov/pubmed/35993367
http://dx.doi.org/10.1172/jci.insight.153058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462497/
https://www.ncbi.nlm.nih.gov/pubmed/35993367
http://dx.doi.org/10.1172/jci.insight.153058

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