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KLF4 is a therapeutically tractable brake on fibroblast activation that promotes resolution of pulmonary fibrosis
There is a paucity of information about potential molecular brakes on the activation of fibroblasts that drive tissue fibrosis. The transcription factor Krüppel-like factor 4 (KLF4) is best known as a determinant of cell stemness and a tumor suppressor. We found that its expression was diminished in...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462506/ https://www.ncbi.nlm.nih.gov/pubmed/35852857 http://dx.doi.org/10.1172/jci.insight.160688 |