Biogeographic and disease-specific alterations in epidermal lipid composition and single-cell analysis of acral keratinocytes

The epidermis is the outermost layer of skin. Here, we used targeted lipid profiling to characterize the biogeographic alterations of human epidermal lipids across 12 anatomically distinct body sites, and we used single-cell RNA-Seq to compare keratinocyte gene expression at acral and nonacral sites...

Descripción completa

Detalles Bibliográficos
Autores principales: Merleev, Alexander A., Le, Stephanie T., Alexanian, Claire, Toussi, Atrin, Xie, Yixuan, Marusina, Alina I., Watkins, Steven M., Patel, Forum, Billi, Allison C., Wiedemann, Julie, Izumiya, Yoshihiro, Kumar, Ashish, Uppala, Ranjitha, Kahlenberg, J. Michelle, Liu, Fu-Tong, Adamopoulos, Iannis E., Wang, Elizabeth A., Ma, Chelsea, Cheng, Michelle Y., Xiong, Halani, Kirane, Amanda, Luxardi, Guillaume, Andersen, Bogi, Tsoi, Lam C., Lebrilla, Carlito B., Gudjonsson, Johann E., Maverakis, Emanual
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Resource and Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462509/
https://www.ncbi.nlm.nih.gov/pubmed/35900871
http://dx.doi.org/10.1172/jci.insight.159762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462509/
https://www.ncbi.nlm.nih.gov/pubmed/35900871
http://dx.doi.org/10.1172/jci.insight.159762

Ejemplares similares