Arginine Deprivation in SCLC: Mechanisms and Perspectives for Therapy

Arginine deprivation has gained increasing traction as a novel and safe antimetabolite strategy for the treatment of several hard-to-treat cancers characterised by a critical dependency on arginine. Small cell lung cancer (SCLC) displays marked arginine auxotrophy due to inactivation of the rate-lim...

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Detalles Bibliográficos
Autores principales: Carpentier, Joséphine, Pavlyk, Iuliia, Mukherjee, Uma, Hall, Peter E, Szlosarek, Peter W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462517/
https://www.ncbi.nlm.nih.gov/pubmed/36091646
http://dx.doi.org/10.2147/LCTT.S335117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462517/
https://www.ncbi.nlm.nih.gov/pubmed/36091646
http://dx.doi.org/10.2147/LCTT.S335117

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