Transient RNA structures cause aberrant influenza virus replication and innate immune activation

During infection, the influenza A virus RNA polymerase produces both full-length and aberrant RNA molecules, such as defective viral genomes (DVGs) and mini viral RNAs (mvRNAs). Subsequent innate immune activation involves the binding of host pathogen receptor retinoic acid–inducible gene I (RIG-I)...

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Detalles Bibliográficos
Autores principales: French, Hollie, Pitré, Emmanuelle, Oade, Michael S., Elshina, Elizaveta, Bisht, Karishma, King, Alannah, Bauer, David L.V., te Velthuis, Aartjan J.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462681/
https://www.ncbi.nlm.nih.gov/pubmed/36083899
http://dx.doi.org/10.1126/sciadv.abp8655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462681/
https://www.ncbi.nlm.nih.gov/pubmed/36083899
http://dx.doi.org/10.1126/sciadv.abp8655

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