The core PCP protein Prickle2 regulates axon number and AIS maturation by binding to AnkG and modulating microtubule bundling

Core planar cell polarity (PCP) genes, which are involved in various neurodevelopmental disorders such as neural tube closure, epilepsy, and autism spectrum disorder, have poorly defined molecular signatures in neurons, mostly synapse-centric. Here, we show that the core PCP protein Prickle-like pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Dorrego-Rivas, Ana, Ezan, Jerome, Moreau, Maïté M., Poirault-Chassac, Sonia, Aubailly, Nathalie, De Neve, Julie, Blanchard, Camille, Castets, Francis, Fréal, Amélie, Battefeld, Arne, Sans, Nathalie, Montcouquiol, Mireille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462691/
https://www.ncbi.nlm.nih.gov/pubmed/36083912
http://dx.doi.org/10.1126/sciadv.abo6333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462691/
https://www.ncbi.nlm.nih.gov/pubmed/36083912
http://dx.doi.org/10.1126/sciadv.abo6333

Ejemplares similares