Cross-fitted instrument: A blueprint for one-sample Mendelian randomization

Bias from weak instruments may undermine the ability to estimate causal effects in instrumental variable regression (IVR). We present here a new approach to handling weak instrument bias through the application of a new type of instrumental variable coined ‘Cross-Fitted Instrument’ (CFI). CFI splits...

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Detalles Bibliográficos
Autores principales: Denault, William R. P., Bohlin, Jon, Page, Christian M., Burgess, Stephen, Jugessur, Astanand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462731/
https://www.ncbi.nlm.nih.gov/pubmed/36037248
http://dx.doi.org/10.1371/journal.pcbi.1010268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462731/
https://www.ncbi.nlm.nih.gov/pubmed/36037248
http://dx.doi.org/10.1371/journal.pcbi.1010268

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