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A novel logical model of COVID-19 intracellular infection to support therapies development

In this paper, a logical-based mathematical model of the cellular pathways involved in the COVID-19 infection has been developed to study various drug treatments (single or in combination), in different illness scenarios, providing insights into their mechanisms of action. Drug simulations suggest t...

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Detalles Bibliográficos
Autores principales: Piretto, Elena, Selvaggio, Gianluca, Bragantini, Damiano, Domenici, Enrico, Marchetti, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462742/
https://www.ncbi.nlm.nih.gov/pubmed/36037223
http://dx.doi.org/10.1371/journal.pcbi.1010443