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CCT196969 effectively inhibits growth and survival of melanoma brain metastasis cells

Melanomas frequently metastasize to the brain. Despite recent progress in the treatment of melanoma brain metastasis, therapy resistance and relapse of disease remain unsolved challenges. CCT196969 is a SRC family kinase (SFK) and Raf proto-oncogene, serine/threonine kinase (RAF) inhibitor with docu...

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Detalles Bibliográficos
Autores principales: Reigstad, Agathe, Herdlevær, Christina Frantzen, Rigg, Emma, Hoang, Tuyen, Bjørnstad, Ole Vidhammer, Aasen, Synnøve Nymark, Preis, Jasmin, Haan, Claude, Sundstrøm, Terje, Thorsen, Frits
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462752/
https://www.ncbi.nlm.nih.gov/pubmed/36084109
http://dx.doi.org/10.1371/journal.pone.0273711