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A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature

Chronic inflammation and blood–brain barrier dysfunction are key pathological hallmarks of neurological disorders such as multiple sclerosis, Alzheimer’s disease and Parkinson’s disease. Major drivers of these pathologies include pro-inflammatory stimuli such as prostaglandins, which are produced in...

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Detalles Bibliográficos
Autores principales: Kemble, Alicia M., Hornsperger, Benoit, Ruf, Iris, Richter, Hans, Benz, Jörg, Kuhn, Bernd, Heer, Dominik, Wittwer, Matthias, Engelhardt, Britta, Grether, Uwe, Collin, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462760/
https://www.ncbi.nlm.nih.gov/pubmed/36084029
http://dx.doi.org/10.1371/journal.pone.0268590