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Desformylflustrabromine (dFBr), a positive allosteric modulator of α(4)β(2) nicotinic acetylcholine receptors decreases voluntary ethanol consumption and preference in male and female Sprague-Dawley rats

Alcohol use disorder is a medical condition that impacts millions of individuals worldwide. Although there are a few pharmacotherapeutic options for alcohol-dependent individuals; there is a need for the development of novel and more effective therapeutic approaches. Alcohol and nicotine are commonl...

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Detalles Bibliográficos
Autores principales: Decker, Steven, Davis, Gregory, Vahora, Imran, Vukovic, Alen, Patel, Parth, Suryanarayanan, Asha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462806/
https://www.ncbi.nlm.nih.gov/pubmed/36084045
http://dx.doi.org/10.1371/journal.pone.0273715