Cargando…
Desformylflustrabromine (dFBr), a positive allosteric modulator of α(4)β(2) nicotinic acetylcholine receptors decreases voluntary ethanol consumption and preference in male and female Sprague-Dawley rats
Alcohol use disorder is a medical condition that impacts millions of individuals worldwide. Although there are a few pharmacotherapeutic options for alcohol-dependent individuals; there is a need for the development of novel and more effective therapeutic approaches. Alcohol and nicotine are commonl...
Autores principales: | Decker, Steven, Davis, Gregory, Vahora, Imran, Vukovic, Alen, Patel, Parth, Suryanarayanan, Asha |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462806/ https://www.ncbi.nlm.nih.gov/pubmed/36084045 http://dx.doi.org/10.1371/journal.pone.0273715 |
Ejemplares similares
-
LY2087101 and dFBr share transmembrane binding sites in the (α4)3(β2)2 Nicotinic Acetylcholine Receptor
por: Deba, Farah, et al.
Publicado: (2018) -
Desformylflustrabromine, a positive allosteric modulator of α4β2-containing nicotinic acetylcholine receptors, enhances cognition in rats
por: Nikiforuk, Agnieszka, et al.
Publicado: (2020) -
Orthosteric and Allosteric Ligands of Nicotinic Acetylcholine Receptors for Smoking Cessation
por: Mohamed, Tasnim S., et al.
Publicado: (2015) -
Recent Advances in the Discovery of Nicotinic Acetylcholine Receptor Allosteric Modulators
por: Manetti, Dina, et al.
Publicado: (2023) -
Influence of perinatal nicotine administration on transplacental carcinogenesis in Sprague Dawley rats by N-methylnitrosourea.
por: Berger, M. R., et al.
Publicado: (1987)