A multi-objective based clustering for inferring BCR clonal lineages from high-throughput B cell repertoire data

The adaptive B cell response is driven by the expansion, somatic hypermutation, and selection of B cell clonal lineages. A high number of clonal lineages in a B cell population indicates a highly diverse repertoire, while clonal size distribution and sequence diversity reflect antigen selective pres...

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Detalles Bibliográficos
Autores principales: Abdollahi, Nika, Jeusset, Lucile, De Septenville, Anne Langlois, Ripoche, Hugues, Davi, Frédéric, Bernardes, Juliana Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462827/
https://www.ncbi.nlm.nih.gov/pubmed/36037250
http://dx.doi.org/10.1371/journal.pcbi.1010411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462827/
https://www.ncbi.nlm.nih.gov/pubmed/36037250
http://dx.doi.org/10.1371/journal.pcbi.1010411

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