Uncoupling of platelet granule release and integrin activation suggests GPIIb/IIIa as a therapeutic target in COVID-19

Thromboembolic events are frequent and life-threating complications of COVID-19 but are also observed in patients with sepsis. Disseminated thrombosis can occur despite anticoagulation, suggesting that platelets play a direct but incompletely understood role. Several studies demonstrated altered pla...

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Detalles Bibliográficos
Autores principales: Weiss, Lukas J., Drayss, Maria, Manukjan, Georgi, Zeitlhöfler, Maximilian, Kleiss, Judith, Weigel, Mathis, Herrmann, Johannes, Mott, Kristina, Beck, Sarah, Burkard, Philipp, Lâm, Thiên-Trí, Althaus, Karina, Bakchoul, Tamam, Frantz, Stefan, Meybohm, Patrick, Nieswandt, Bernhard, Weismann, Dirk, Schulze, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462922/
https://www.ncbi.nlm.nih.gov/pubmed/36053793
http://dx.doi.org/10.1182/bloodadvances.2022008666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462922/
https://www.ncbi.nlm.nih.gov/pubmed/36053793
http://dx.doi.org/10.1182/bloodadvances.2022008666

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