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The paradigm of immune escape by SARS-CoV-2 variants and strategies for repositioning subverted mAbs against escaped VOCs

The perpetual emergence of SARS-CoV-2 variants is a serious issue that makes it difficult for the therapeutic antibodies and vaccines to end the COVID-19 pandemic. This article discusses the trend of increasing host fitness and immune escape by the virus and how to devise computational strategies fo...

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Detalles Bibliográficos
Autores principales: Shah, Masaud, Woo, Hyun Goo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462941/
https://www.ncbi.nlm.nih.gov/pubmed/36087577
http://dx.doi.org/10.1016/j.ymthe.2022.08.020