Association of Cytotoxic T-Lymphocyte Antigen-4 Gene Polymorphism with Type 1 Diabetes Mellitus: In silico Analysis of Biological Features of CTLA-4 Protein on Ethiopian Population

BACKGROUND: T1DM is a chronic organ-specific T-cell-mediated autoimmune disease characterized by the selective destruction of β-cells in the islets of Langerhans, resulting in insulin deficiency and hyperglycemia. Genes for cytotoxic T lymphocyte-associated antigen 4 have been hypothesized as possib...

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Detalles Bibliográficos
Autores principales: Ebrahim, Endris, Teklu, Takele, Tajebe, Fitsumbrhan, Wondmagegn, Tadelo, Akelew, Yibeltal, Fiseha, Mesfin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462946/
https://www.ncbi.nlm.nih.gov/pubmed/36091481
http://dx.doi.org/10.2147/DMSO.S375023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462946/
https://www.ncbi.nlm.nih.gov/pubmed/36091481
http://dx.doi.org/10.2147/DMSO.S375023

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