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Application of Melatonin with N-Acetylcysteine Exceeds Traditional Treatment for Acetaminophen-Induced Hepatotoxicity

Acetaminophen (APAP) overdose is one of the leading causes of acute liver damage. Given N-acetylcysteine (NAC) and melatonin (MLT) both have an attenuated value for APAP-induced liver toxification, where an optimized integrated treatment has not been well deciphered. Here, by giving a single dose of...

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Detalles Bibliográficos
Autores principales: Chen, Mengfei, Ke, Jinfang, Ma, Shilan, Chai, Hua, Zhang, Liang, Zhang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463034/
https://www.ncbi.nlm.nih.gov/pubmed/36090543
http://dx.doi.org/10.1155/2022/2791743