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SLITRK1-mediated noradrenergic projection suppression in the neonatal prefrontal cortex

SLITRK1 is an obsessive-compulsive disorder spectrum-disorders-associated gene that encodes a neuronal transmembrane protein. Here we show that SLITRK1 suppresses noradrenergic projections in the neonatal prefrontal cortex, and SLITRK1 functions are impaired by SLITRK1 mutations in patients with sch...

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Detalles Bibliográficos
Autores principales: Hatayama, Minoru, Katayama, Kei-ichi, Kawahara, Yukie, Matsunaga, Hayato, Takashima, Noriko, Iwayama, Yoshimi, Matsumoto, Yoshifumi, Nishi, Akinori, Yoshikawa, Takeo, Aruga, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463131/
https://www.ncbi.nlm.nih.gov/pubmed/36085162
http://dx.doi.org/10.1038/s42003-022-03891-y