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Structure and function of H(+)/K(+) pump mutants reveal Na(+)/K(+) pump mechanisms

Ion-transport mechanisms evolve by changing ion-selectivity, such as switching from Na(+) to H(+) selectivity in secondary-active transporters or P-type-ATPases. Here we study primary-active transport via P-type ATPases using functional and structural analyses to demonstrate that four simultaneous r...

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Detalles Bibliográficos
Autores principales: Young, Victoria C., Nakanishi, Hanayo, Meyer, Dylan J., Nishizawa, Tomohiro, Oshima, Atsunori, Artigas, Pablo, Abe, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463140/
https://www.ncbi.nlm.nih.gov/pubmed/36085139
http://dx.doi.org/10.1038/s41467-022-32793-0