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AAV2/9-mediated gene transfer into murine lacrimal gland leads to a long-term targeted tear film modification

Corneal blindness is the fourth leading cause of blindness worldwide. Since corneal epithelium is constantly renewed, non-integrative gene transfer cannot be used to treat corneal diseases. In many of these diseases, the tear film is defective. Tears are a complex biological fluid secreted by the la...

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Detalles Bibliográficos
Autores principales: Gautier, Benoit, Meneux, Léna, Feret, Nadège, Audrain, Christine, Hudecek, Laetitia, Kuony, Alison, Bourdon, Audrey, Le Guiner, Caroline, Blouin, Véronique, Delettre, Cécile, Michon, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463184/
https://www.ncbi.nlm.nih.gov/pubmed/36156877
http://dx.doi.org/10.1016/j.omtm.2022.08.006