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AAV2/9-mediated gene transfer into murine lacrimal gland leads to a long-term targeted tear film modification
Corneal blindness is the fourth leading cause of blindness worldwide. Since corneal epithelium is constantly renewed, non-integrative gene transfer cannot be used to treat corneal diseases. In many of these diseases, the tear film is defective. Tears are a complex biological fluid secreted by the la...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463184/ https://www.ncbi.nlm.nih.gov/pubmed/36156877 http://dx.doi.org/10.1016/j.omtm.2022.08.006 |