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Biopsy-based optimization and calibration of a signal-intensity-ratio-based MRI method (1.5 Tesla) in a dextran-iron loaded mini-pig model, enabling estimation of very high liver iron concentrations

OBJECTIVE: Magnetic resonance imaging (MRI)-based techniques for non-invasive assessing liver iron concentration (LIC) in patients with iron overload have a limited upper measuring range around 35 mg/g dry weight, caused by signal loss from accelerated T1-, T2-, T2* shortening with increasing LIC. E...

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Detalles Bibliográficos
Autores principales: Jensen, Peter D., Nielsen, Asbjørn H., Simonsen, Carsten W., Jensen, Kenneth K., Bøgsted, Martin, Jensen, Anne B. H., Kjaergaard, Benedict
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463247/
https://www.ncbi.nlm.nih.gov/pubmed/35038062
http://dx.doi.org/10.1007/s10334-021-00998-x