Silencing Itch in human peripheral blood monocytes promotes their differentiation into osteoclasts

INTRODUCTION: Two clinical case reports of humans with mutations in Itch reported distinct morphological defects such as stunted growth, macrocephaly, and dysmorphic features indicating a role for Itch in bone remodelling. Studies in mice have found that the encoded E3 ubiquitin ligase acts as a neg...

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Detalles Bibliográficos
Autores principales: Read, O. J., Harrison, D. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463264/
https://www.ncbi.nlm.nih.gov/pubmed/35793050
http://dx.doi.org/10.1007/s11033-022-07726-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463264/
https://www.ncbi.nlm.nih.gov/pubmed/35793050
http://dx.doi.org/10.1007/s11033-022-07726-1

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