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Bevacizumab and sunitinib mediate osteogenic and pro-inflammatory molecular changes in primary human alveolar osteoblasts in vitro

Antiangiogenic medications target the de novo blood vessel formation in tumorigenesis. However, these novel drugs have been linked to the onset of medication-related osteonecrosis of the jaw (MRONJ). The aim of this in vitro study was to examine the effects of the vascular endothelial growth factor...

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Detalles Bibliográficos
Autores principales: Hofmann, Elena, Eggers, Benedikt, Heim, Nils, Kramer, Franz-Josef, Nokhbehsaim, Marjan, Götz, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463285/
https://www.ncbi.nlm.nih.gov/pubmed/35171372
http://dx.doi.org/10.1007/s10266-022-00691-y