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Cellular and soluble immune checkpoint signaling forms PD-L1 and PD-1 in renal tumor tissue and in blood

Immune checkpoint blockade therapy is a treatment option of various metastatic cancer diseases including renal cell carcinoma (RCC). Approved antibody drugs target the co-inhibitory signaling of Programmed Cell Death Ligand-1 (PD-L1) and its receptor Programmed Cell Death-1 (PD-1). The combined eval...

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Detalles Bibliográficos
Autores principales: Keber, Corinna U., Derigs, Marcus, Schultz, Carolin, Wegner, Moritz, Lingelbach, Susanne, Wischmann, Viktoria, Hofmann, Rainer, Denkert, Carsten, Hegele, Axel, Hänze, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463294/
https://www.ncbi.nlm.nih.gov/pubmed/35184226
http://dx.doi.org/10.1007/s00262-022-03166-9