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TOP2B Is Required to Maintain the Adrenergic Neural Phenotype and for ATRA-Induced Differentiation of SH-SY5Y Neuroblastoma Cells

The neuroblastoma cell line SH-SY5Y is widely used to study retinoic acid (RA)-induced gene expression and differentiation and as a tool to study neurodegenerative disorders. SH-SY5Y cells predominantly exhibit adrenergic neuronal properties, but they can also exist in an epigenetically interconvert...

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Detalles Bibliográficos
Autores principales: Khazeem, Mushtaq M., Casement, John W., Schlossmacher, George, Kenneth, Niall S., Sumbung, Nielda K., Chan, Janice Yuen Tung, McGow, Jade F., Cowell, Ian G., Austin, Caroline A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463316/
https://www.ncbi.nlm.nih.gov/pubmed/35831557
http://dx.doi.org/10.1007/s12035-022-02949-6