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Adenosine A(2A) Receptor Blockade Ameliorates Mania Like Symptoms in Rats: Signaling to PKC-α and Akt/GSK-3β/β-Catenin

Adenosinergic system dysfunction is implicated in the pathophysiology of multiple neuropsychiatric disorders including mania and bipolar diseases. The established synergistic interaction between A(2A) and D(2) receptors in the prefrontal cortex could highlight the idea of A(2A) receptor antagonism a...

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Detalles Bibliográficos
Autores principales: Shalaby, Heba Nasr, Zaki, Hala Fahmy, Ain-Shoka, Afaf Abd Almonim, Mohammed, Reham Atef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463338/
https://www.ncbi.nlm.nih.gov/pubmed/35943710
http://dx.doi.org/10.1007/s12035-022-02977-2