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Adenosine A(2A) Receptor Blockade Ameliorates Mania Like Symptoms in Rats: Signaling to PKC-α and Akt/GSK-3β/β-Catenin
Adenosinergic system dysfunction is implicated in the pathophysiology of multiple neuropsychiatric disorders including mania and bipolar diseases. The established synergistic interaction between A(2A) and D(2) receptors in the prefrontal cortex could highlight the idea of A(2A) receptor antagonism a...
Autores principales: | Shalaby, Heba Nasr, Zaki, Hala Fahmy, Ain-Shoka, Afaf Abd Almonim, Mohammed, Reham Atef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463338/ https://www.ncbi.nlm.nih.gov/pubmed/35943710 http://dx.doi.org/10.1007/s12035-022-02977-2 |
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