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Functional association of NR4A3 downregulation with impaired differentiation in myeloid leukemogenesis

The coincident downregulation of NR4A1 and NR4A3 has been implicated in myeloid leukemogenesis, but it remains unknown how these two genes function in myeloid cells and how their combined downregulation promotes myeloid leukemogenesis. Since NR4A1 abrogation is thought to confer a survival and proli...

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Detalles Bibliográficos
Autores principales: Lin, Shih-Chiang, Yao, Chi-Yuan, Hsu, Cheng-An, Lin, Chien-Ting, Calkins, Marcus J., Kuo, Yuan-Yeh, Tang, Jih-Luh, Tien, Hwei-Fang, Wu, Shang-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463347/
https://www.ncbi.nlm.nih.gov/pubmed/36040481
http://dx.doi.org/10.1007/s00277-022-04961-1