Cargando…

Functional association of NR4A3 downregulation with impaired differentiation in myeloid leukemogenesis

The coincident downregulation of NR4A1 and NR4A3 has been implicated in myeloid leukemogenesis, but it remains unknown how these two genes function in myeloid cells and how their combined downregulation promotes myeloid leukemogenesis. Since NR4A1 abrogation is thought to confer a survival and proli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Shih-Chiang, Yao, Chi-Yuan, Hsu, Cheng-An, Lin, Chien-Ting, Calkins, Marcus J., Kuo, Yuan-Yeh, Tang, Jih-Luh, Tien, Hwei-Fang, Wu, Shang-Ju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463347/ https://www.ncbi.nlm.nih.gov/pubmed/36040481 http://dx.doi.org/10.1007/s00277-022-04961-1

Ejemplares similares

The distinct biological implications of Asxl1 mutation and its roles in leukemogenesis revealed by a knock-in mouse model
por: Hsu, Yueh-Chwen, et al.
Publicado: (2017)

Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemia
por: Hou, Hsin-An, et al.
Publicado: (2016)

High Risk of Hepatitis B Reactivation among Patients with Acute Myeloid Leukemia
por: Chen, Chien-Yuan, et al.
Publicado: (2015)

RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia
por: Bera, Rabindranath, et al.
Publicado: (2019)

Incorporation of long non-coding RNA expression profile in the 2017 ELN risk classification can improve prognostic prediction of acute myeloid leukemia patients
por: Tsai, Cheng-Hong, et al.
Publicado: (2019)

Long non-coding RNA HOXB-AS3 promotes myeloid cell proliferation and its higher expression is an adverse prognostic marker in patients with acute myeloid leukemia and myelodysplastic syndrome
por: Huang, Huai-Hsuan, et al.
Publicado: (2019)

GATA2 zinc finger 1 mutations are associated with distinct clinico-biological features and outcomes different from GATA2 zinc finger 2 mutations in adult acute myeloid leukemia
por: Tien, Feng-Ming, et al.
Publicado: (2018)

Prognostic impacts and dynamic changes of cohesin complex gene mutations in de novo acute myeloid leukemia
por: Tsai, Cheng-Hong, et al.
Publicado: (2017)

Risk factors and clinical outcomes of acute myeloid leukaemia with central nervous system involvement in adults
por: Cheng, Chieh-Lung, et al.
Publicado: (2015)

RAF Kinase Inhibitor Protein in Myeloid Leukemogenesis
por: Zebisch, Armin, et al.
Publicado: (2019)

Clinical and Prognostic Implications of Roundabout 4 (Robo4) in Adult Patients with Acute Myeloid Leukemia
por: Chen, Yin-Kai, et al.
Publicado: (2015)

Clinicopathologic features and responses to radiotherapy of myeloid sarcoma
por: Chen, Wan-Yu, et al.
Publicado: (2013)

H19 overexpression promotes leukemogenesis and predicts unfavorable prognosis in acute myeloid leukemia
por: Zhang, Ting-juan, et al.
Publicado: (2018)

Mechanisms of myeloid leukemogenesis: Current perspectives and therapeutic objectives
por: Bouligny, Ian M., et al.
Publicado: (2023)

Hepatitis B reactivation among 1962 patients with hematological malignancy in Taiwan
por: Chen, Chien-Yuan, et al.
Publicado: (2018)

Hierarchical cluster analysis of immunophenotype classify AML patients with NPM1 gene mutation into two groups with distinct prognosis
por: Chen, Chien-Yuan, et al.
Publicado: (2013)

ASXL1 mutation confers poor prognosis in primary myelofibrosis patients with low JAK2V617F allele burden but not in those with high allele burden
por: Wang, Yu-Hung, et al.
Publicado: (2020)

Role of Nucleophosmin Gene Mutation in Leukemogenesis of Acute Myeloid Leukemia
por: Khaled, Safaa A.A., et al.
Publicado: (2018)

Altered expression of imprinted genes in patients with cytogenetically normal‑acute myeloid leukemia: Implications for leukemogenesis and survival outcomes
por: Yang, Ming-Yu, et al.
Publicado: (2023)

Dynamics of DNMT3A mutation and prognostic relevance in patients with primary myelodysplastic syndrome
por: Lin, Ming-En, et al.
Publicado: (2018)

Distinct molecular genetics of chronic lymphocytic leukemia in Taiwan: clinical and pathogenetic implications
por: Wu, Shang-Ju, et al.
Publicado: (2017)

Distinct mutation profile and prognostic relevance in patients with hypoplastic myelodysplastic syndromes (h-MDS)
por: Yao, Chi-Yuan, et al.
Publicado: (2016)

A nucleolin-DNMT1 regulatory axis in acute myeloid leukemogenesis
por: Shen, Na, et al.
Publicado: (2014)

The process of leukemogenesis.
por: Irons, R D, et al.
Publicado: (1996)

Invasive fungal sinusitis in patients with hematological malignancy: 15 years experience in a single university hospital in Taiwan
por: Chen, Chien-Yuan, et al.
Publicado: (2011)

Intracranial hemorrhage in adult patients with hematological malignancies
por: Chen, Chien-Yuan, et al.
Publicado: (2012)

Clinical characteristics and outcomes of Mycobacterium tuberculosis disease in adult patients with hematological malignancies
por: Chen, Chien-Yuan, et al.
Publicado: (2011)

Clinically validated machine learning algorithm for detecting residual diseases with multicolor flow cytometry analysis in acute myeloid leukemia and myelodysplastic syndrome
por: Ko, Bor-Sheng, et al.
Publicado: (2018)

Methylation-associated silencing of BASP1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia
por: Zhou, Lei, et al.
Publicado: (2018)

The Possible Importance of β3 Integrins for Leukemogenesis and Chemoresistance in Acute Myeloid Leukemia
por: Johansen, Silje, et al.
Publicado: (2018)

Tet1 is not required for myeloid leukemogenesis by MLL-ENL in novel mouse models
por: Ono, Ryoichi, et al.
Publicado: (2021)

High Incidences of Invasive Fungal Infections in Acute Myeloid Leukemia Patients Receiving Induction Chemotherapy without Systemic Antifungal Prophylaxis: A Prospective Observational Study in Taiwan
por: Tang, Jih-Luh, et al.
Publicado: (2015)

Distinct clinical and biological characteristics of acute myeloid leukemia with higher expression of long noncoding RNA KIAA0125
por: Wang, Yu-Hung, et al.
Publicado: (2020)

The Philadelphia chromosome in leukemogenesis
por: Kang, Zhi-Jie, et al.
Publicado: (2016)

Incorporation of mutations in five genes in the revised International Prognostic Scoring System can improve risk stratification in the patients with myelodysplastic syndrome
por: Hou, Hsin-An, et al.
Publicado: (2018)

Expression of cereblon protein assessed by immunohistochemicalstaining in myeloma cells is associated with superior response of thalidomide- and lenalidomide-based treatment, but not bortezomib-based treatment, in patients with multiple myeloma
por: Huang, Shang-Yi, et al.
Publicado: (2014)

P721: VALIDATION OF THE MOLECULAR INTERNATIONAL PROGNOSTIC SCORING SYSTEM IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES DEFINED BY INTERNATIONAL CONSENSUS CLASSIFICATION
por: Hsuan Lee, Wan, et al.
Publicado: (2023)

Impaired DNA Replication within Progenitor Cell Pools Promotes Leukemogenesis
por: Bilousova, Ganna, et al.
Publicado: (2005)

Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia
por: Lee-Sherick, A B, et al.
Publicado: (2013)

The PIM family of oncoproteins: Small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets
por: Saurabh, Kumar, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_016bhg61o1u3a32brcac0566l8