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The mGlu(5) Receptor Protomer-Mediated Dopamine D(2) Receptor Trans-Inhibition Is Dependent on the Adenosine A(2A) Receptor Protomer: Implications for Parkinson’s Disease

The adenosine A(2A) receptor (A(2A)R), dopamine D(2) receptor (D(2)R) and metabotropic glutamate receptor type 5 (mGluR(5)) form A(2A)R-D(2)R-mGluR(5) heteroreceptor complexes in living cells and in rat striatal neurons. In the current study, we present experimental data supporting the view that the...

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Detalles Bibliográficos
Autores principales: Romero-Fernandez, Wilber, Taura, Jaume J., Crans, René A. J., Lopez-Cano, Marc, Fores-Pons, Ramon, Narváez, Manuel, Carlsson, Jens, Ciruela, Francisco, Fuxe, Kjell, Borroto-Escuela, Dasiel O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463353/
https://www.ncbi.nlm.nih.gov/pubmed/35829830
http://dx.doi.org/10.1007/s12035-022-02946-9